|
Author: Christopher Ruane Article source: http://www.kabish.com/. Used with author's permission.
Have you ever taken the drug Vioxx or celebrex?
In September 2004 the drug manufacturer Merck decided
to recall the product after long term data suggested
a serious potential side effect.
This drug and others like it such as as 'Celebrex',
'Bextra' and 'Arcoxia' are part of a family of drugs
known as "COX2 drugs" or "COX2 inhibitors"
They have been developed with, ironically, patient safety
in mind.They are typically used in treatment of arthritis,
though high dose vioxx was promoted for short term relief
of acute muscular/skeletal pains.They were anti-inflammatory
drugs.
The serious side effects were in connection with the heart
suggesting risk of heart disease or heart attack.In medical
circles it was referred to as "..adverse cardiovascular effects."
There are other drugs used to treat inflammation that have been
around for many years.YOu may have heard of products such as
Advil or Nurofen which contain the ingredient Ibuprofen.Other
older anti-inflammatory drugs include such brands as Voltarol
or Naprosyn.
What's the difference between these older drugs and the recent
treatments know as "COX2 drugs"?
The newer drugs such as Arcoxia,Celebrex and Vioxx were designed
to be much more specific in their mode action than old drugs
like Ibuprofen.The idea was to limit the associated problems
in long term treatment.
When we get older we all seem to get more sensitive to side
effects of drugs.Often this is complicated even more by the
fact that we may suffer from more than one problem or disease
at the same time.
At this point we take more medication in the last five to ten
years of our lives than in all the other years put together!
Is it any wonder we might feel under the weather, a little off
colour even?
You could have asthma and high blood pressure.
Anxiety and lack of sleep every night.
Panic attacks and depression.
If you take an anti-inflammatory drug for a given length of
time, your doctor/physician will no doubt tell you about
one major problem.
Ulceration of the stomach or intestines.....
It was hoped that the newer COX2 drugs would not cause this
problem at all.Therefore it would avoid the risk of someone
suffering internal bleeding which could become fatal.
The older you become the greater the risk of this occuring.
It could be a slow blood loss or a sudden episode of an ulcer
bleeding more profusely.
So when people got the signs of ulcers, they got treatment
for an ulcer. Some would stop taking medication and others
would take a maintenance dose to prevent ulcers coming back
while continuing to take the old ibuprofen drugs for their
arthritis.
It was hoped drugs like vioxx would stop this, but ulceration
still remains a possibility. Doctors routinely consider offering
anti ulcer drugs to reduce the probability of this happening.
So what is the all the recent fuss about ? Where did it all
suddenly seem to unravel after all that hope and expectation ?
A new long term study seemed to indicate some degree of risk
to the heart some 18 months or so after starting treatment.
So if you took vioxx for a week or a couple of months, this
potential problem did not appear.It has only been spotted
after taking the medication for a longer period such as
18 months.
What can you do? Are there ways to reduce risks?
This is something you need advice on as only your doctor will
have your medical history.There is much to consider and such
a problem can in some circumstances be minimised.
Of course if you smoke you increase the risk of stomach
or intestinal ulceration if you also take anti-inflammatory
drugs such as Ibuprofen.Why not quit instead?
If you take other medication for depression or anxiety then
these drugs can increase the risk of bleeding with any
anti-inflammatory drug being taken at the same time. For more related information visit
http://www.AnxietyAttacksCure.com - a site that offers
advice for avoiding, coping with anxiety and panic attacks.
Get professional knowledge on dealing with symptoms,
drug side effects and improving your life!
Improving Cellular Communication With Glyconutrients
A look into an area of nutrition that facilitates cell-to-cell communcation.
Using a Camcorder to Record Family Events Quickly and Easily
Chances are your video camera has more buttons on it than you wish it did. To use it you need to know where about four buttons are -- you may be able to take st...
Marketers VS Consumers Predators VS Prey
Marketing that generates badwill in prospects...
Spice Up Your Bedroom With Paint
Afraid to paint your bedroom walls with color? What holds you back? Are you afraid the color will be too strong? Not match your furniture? Or you'll become tir...
Timing Is Everything - Part 1
In this series of articles we're going to take a good hard look at timing. In other words, to really rocket our fat-loss results into the stratosphere, we absol...
Designing Beautiful Artist Websites – 12 Tips To Showcase Your Art
Here's the scoop on what things you must know when designing a website to
showcase your art, impress galleries and win over collectors. Learn how to avoid the ...
How to Ensure You Receive Top Quality Business Cards Online
Tailor-made products are hard enough to order face-to-face. Jonathan Bowalsky provides helpful tips to ordering quality business cards online.
Improve Golf Swing The Non-Traditional Way
Improve golf swing seems like a thought that is on our minds as golfers dozens of times per day. Do you agree? But what are you currently doing to improve you...
Why PR Can be Effective Medicine
It's easy-to-swallow "medicine" when it leads managers to persuade those key outside folks to their way of thinking.
So, You Wanna Buy Pre-Foreclosures?
So you wanna buy pre-foreclosures? or at the courthouse steps? So many people ask us about this. Here's our '30 second seminar' on it. If you're going to bu...
The Man - Truth of The Visual Being
The article What Turns Them On explained about how men are visual being towards a woman's beauty. But don't go off thinking that all men are shallow just yet. T...
Cialis Basics
Sex has been the part of the life since the day Adam saw the apple. Man has been striving to achieve a better performance in order to satisfy both his as well h...
Top Ten Ways to Promote Your Website When the Traffic Dries Up
Traffic Generation Tips to Jump Start Your Website Stats and Increase Your Targeted Visitors
How To Properly Check The Club Heads Of Second Swing Used Golf Club
I wrote this article on how to properly check the clubheads of Second Swing used golf clubs. This is vital task so you get a good quality and good performing Se...
Space Probes Speed Up
Recently scientists were amazed that the space probes now leaving our solar system suddenly started to speed up? They should not be surprised because the gravi...
Cellular Phone Accessory
There is a wide variety of products that belong to the cellular phone accessory list. You can find any cellular phone accessory that you wish to buy sold at var...
Why Should You Take Urine Test in the Morning?
Okay, don't get so worried or happy when your monthly period stops! Your pregnancy depend on the test you going to take. You need to find pregnancy test kit to ...
Pregnancy and Tanning Beds
With summer approaching, you would love to wear those cute maternity sun dresses, but you don't want to show off your...
Five Credit Card Billing Problems and How to Fix Them
It goes without saying that your first and best defense against paying fraudulent or unfair charges on your credit card is knowing what your bill says! When you...
If I Hurt You, Then Im Sorry
This statement has stopped many a war in my house. My oldest two children are two years apart in age and would fight about everything and nothing when they wer...
Goal-Mapping
6 Simple Steps to Makikng Your Dreams Comes True.
When Good Computers Go Bad
Remember the day that you got your new computer (or the hand-me down from Uncle Larry) and you pulled that shiny case out of the box? Once you finally had all o...
Walt Disney, the Inspiration to Form a Better Life?
You, like many others, may have come to this article because you want more from life. In this sense, you and I may be alike because we're searching for greate...
Build Wealth From Home
Build Wealth From Home As you sit in traffic, inching along between irate drivers, you think to yourself, "there must be a better way." You get to work, you e...
|
Print this page